Microbiological parameters of Amoxil

amoxilAmoxicillin has the same bactericidal effect as ampicillin. It is bactericidal against bacterial organisms when they are actively dividing. The medicine stops the biosynthesis of cell walls and thus prevents the development of the disease.
In vitro and in vivo Amoxicillin has been proven to be active against the strains of the following microorganisms:
Aerobic Gram-Positive Microorganisms
•    Enterococcus faecalis
•    Staphylococcus spp.
•    Streptococcus pneumoniae
•    Streptococcus spp.
•    Staphylococci susceptible to amoxicillin
Aerobic Gram-Negative Microorganisms
•    Escherichia coli
•    Haemophilus influenzae
•    Neisseria gonorrhoeae
•    Proteus mirabilis
Helicobacter pylori
Various types of infectious diseases caused by bacteria are effectively treated with Amoxicillin.

What other medicines will affect clavulanate and Amoxicillin?

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Before taking clavulanate or Amoxicillin, tell your provider if you are using any of the following medicines:

  •   probenecid (Benemid); or
  •   allopurinol (Zyloprim);
  •   another antibiotic (for a different or for the same infection).

The patient may not be able to use clavulanate or Amoxicillin, if he is using any of these medicines, he may need  special tests or dosage adjustments during treatment.
This drug can make birth control pills less effective, because we recommend to use a  diaphragm/condom/spermicide).

Side effects of Amoxil


Evry patient must know that he may side effects and allergic reaction to Amoxil, because very important consult with health care provessional if you want to star take Amoxil.
Serious side effects:

  •  swollen glands,
  •  white patches or sores inside your mouth or on your lips;
  •  confusion or weakness
  •  fever, itching or rash and  general ill feeling;
  •  red skin rash
  •  peeling,
  •  severe blistering,and;
  •  joint pain,
  •  yellowed or pale skin fever, , dark colored urine,;
  •  yellowing of the eyes,
  •  severe tingling, numbness, pain, muscle weakness; or
  •  red/ purple pinpoint spots under your skin, easy bruising,
  •  unusual bleeding (rectum, nose, vagina, mouth ).

Less serious Amoxil side effects may include:

  •  nausea
  •  stomach pain,
  •  vaginal  discharge or  itching;
  •  headache; or
  •  vomiting;
  •  black/swollen/”hairy” tongue.

Review about Amoxicillin

Amoxicillin will help nursing mums, without  harm for the children

Advantages:
A good result. Nursing mums  can also use it.

Disadvantages:
This group of antibiotics often causes allergic reactions.

After childbirth female body needs recovery. During this period immunity decreases. I’m tired from all the ills in the first months of my daughter”s life. And I do not want very much to be ill together with my baby. Not all husbands are able at this time to replace the mother to baby. And give “the poor woman quietly to be ill”.

So. Due to constant illness, it has intensified my herpes virus. Just some bubbles were replaced another bubbles. Consequences for the child may be at best a windmill. In the worst case, it could end up festering sore throat. Very scary.

I was ashamed to go out street and talk with other mums. I walked alone with a stroller, to avoid to infect the other children.

So. Seeing all my suffering, the pediatrician told me to drink these antibiotics. She said that they were allowed in the period of lactation. However, for insurance, the doctor prescribed to give child “Linex”. But I gave nothing. Daughter did not responded to using this drug by me. After this course, herpes did not bothers me.

Amoxicillin: what you must know

If you have amoxicillin tablets without  instruction – it is not attached or lost during storage preparation, do not hurry to open and take internally. First, we suggest to learn with the instruction. This antibiotic has a huge number of contraindications and side effects. It is quite possible that  it is strictly forbidden for you to use amoxicillin. Does amoxicillin have analogs? Yes, there is a huge amount of antibiotics that you can use with less risk to your health. Amoxicillin has  mostly positive reviews. But it is only when the dosage of the drug is chosen wisely and according to the seriousness of the disease.

In modern medical practice persons use most often  amoxicillin 500. This is a fairly stable substance that perfectly preserves its medicinal properties in the acidic environment of gastric juice. Therefore, this drug is often used in the treatment of gastric ulcers.

Amoxicillin belongs to microbicides. This means that the action is not aimed at suppressing the growth and reproduction of pathogenic bacteria. Amoxicillin destroys the cell structure of the harmful bacteria, thus, causing massive destruction. On the one hand it is a very good thing. The patient in a short time  rid from disease-causing agent. But on the other hand the mass destruction of the bacteria causes increased toxicity. You must consider this when use amoxicillin: although the instruction does not say about this.

Amoxicillin and sore throat: dosage

1. Adults and children over 10 years  take amoxicillin: 500 mg 3 times a day.
2. Children from 5 to 10 years:  250 mg 3 times a day.
3. Children under 2 years old – the dosage is calculated as follows: 20 mg of amoxicillin per kilogram of body weight of the child.

Amoxicillin suspension: instruction

1. It is used mostly for the treatment of children under five
2. You should drink plenty of water
3. You must necessarily to use antihistamine a half an hour before taking amoxicillin suspension

Amoxicillin and pregnancy

Is it safe to use amoxicillin during pregnancy?

Medical professionals say that the harmful effect of the drug on the fetus is unlikely, but, despite this, the drug is prescribed only when it is absolutely necessary.

Amoxicillin is considered harmless drug that can be used during pregnancy, in any case, it should not be practiced self-appointed and self-medicate. Such using could have serious violations and threats for the future baby. Of course, in the instruction you will find that this drug is not desirably to take during pregnancy. But do not worry, because no doctor will prescribe it just so, and only if the risk of the disease is higher than the risk of using the drug. All the more, studies have shown that amoxicillin does not influence the fetus and pregnancy. The danger from using  amoxicillin is not in the pathogenic influence  the fetus, and in the risk of hidden bleeding.

To protect yourself and your baby, during taking medication, it is important to follow the precise instructions in the manual. For example, amoxicillin should be used at regular intervals during the day, and each dose should drink with a full glass of water. To swallow the capsule you must entirely, without breaking, without chewing, and not opening. But if you have a drug in pill form, on the contrary,  they should be chewed before swallowing. In case, if amoxicillin suspension was prescribed for you, taking it, use a measuring spoon and never  use a simple spoon.

Amoxicillin / clavulanic acid: safe and reliable antibiotic for the treatment of infectious diseases

The problem of infectious diseases

Treatment of infectious diseases continues to be one of the most frequent problems. Therefore, the choice of the most effective therapeutic agent is also exceptionally actual task.
The international medical community is concerned the rapid growth  diseases of antibiotic-resistant infections caused by micro-organisms that produce extended spectrum beta-lactamases.
Оn the basis of  β-lactams were developed and used сompounded drugs, consisting of β-lactam antibiotics (penicillin group, cephalosporins) and β-lactamase inhibitor (clavulanic acid, sulbactam, tazobactam).

Amoxicillin / clavulanic acid: advantage protected penicillins

An important distinction between protected penicillins (aminopenicillins) from its predecessor ampicillin is the better absorption after oral and the creation of a higher concentration to effectively fight pathogens in tissues and biological fluids . The main advantage of aminopenicillins compared to protected cephalosporins, and macrolides, is the activity against enterococci and anaerobes. Besides,considering  that the reason of community-acquired infections in the 30 – 60% of cases are the streptococcus which are highly sensitive to aminopenicillins, these drugs are the basis of Antimicrobial Chemotherapy, occupying a leading position in the treatment of the most typical infections.
Clavulanic acid has a pronounced activity against important, from the clinical point of view, plasmid beta-lactamases, which are often responsible for the emergence of cross-resistance to antibiotics.

The results of a multicenter, international, monitoring, microbiological studies of Alexander Project led to the combination of amoxicillin / clavulanic acid has been recommended as the drug of the first choice for the treatment of respiratory tract infections.
Amoxicillin / clavulanate has received deserved international recognition – this combination was included in the guidelines  the treatment of respiratory organs in 150 countries. It is one of the most prescribed bacterial agent  in the world for systemic use.

Today the optimal agent in terms of clinical effectiveness, safety and accessibility is amoxicillin, protected by clavulanic acid.

Amoxicillin: description of the drug

Uses:

Amoxicillin is a broad-spectrum antibiotic from the group aminopenicillins, used to treat  bacterial infections, caused by susceptible microorganisms.

Active against such microorganisms as Gram-positive bacteria  Staphylococcus spp. (with the exception of strains producing penicillinase), Streptococcus spp., (including Streptococcus pneumoniae), Bacillus anthracis, Corynebacterium diphtheriae (most strains), Erysipelothrix rhusiopathiae, Listeria monocytogenes; gram-negative bacteria: Borrelia burgdorferi, Escherichia coli, Haemophilus influenzae, Klebsiella spp. , Leptospira spp., Moraxella (Branhamella catarrhalis) (most strains), Neisseria gonorrhoeae, Neisseria meningitidis; Proteus mirabilis, Salmonella spp., Shigella spp., Treponema pallidum, Treponema pertenue; anaerobic bacteria: Eubacterium spp., Clostridium perfringens, Clostridium tetani , Peptostreptococcus spp., Peptococcus spp., Streptococcus faecalis.

Dosage:

After oral amoxicillin is well absorbed, reaching maximum  concentration in the blood serum within 2 hours after acceptance. Excreted unchanged by the kidney (60 – 70%).
For adults and children over 10 years dosing regimens are 250 mg every 8 hours, 500 mg every 8 hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.

Side effects:

• allergic reactions (urticaria, erythema, angioedema, rhinitis, conjunctivitis, and in rare cases, fever, joint pain, eosinophilia, and very rarely anaphylactic shock);
• from the digestive tract (nausea, vomiting, diarrhea), development of superinfections.
When it is used in combination with metronidazole are possible:
• nausea, vomiting, anorexia, diarrhea, constipation, abdominal pain, glossitis, stomatitis, in rare cases, hepatitis, pseudomembranous colitis, interstitial nephritis, hematopoietic disorders;
• long-term use of high doses: dizziness, ataxia, loss of consciousness, depression, recurrent neuropathy, seizures.

Drug interactions:

Amoxicillin reduces the effect of estrogen contraceptives. Enhances the absorption of digoxin. Decreases clearance and increases the toxicity of methotrexate. Excretion by the kidneys is slowed by aspirin, indomethacin, sulfinperazonom, oxyphenbutazone, phenylbutazone.